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Column Chromatography Silica Gel: High-Purity Silica for Separation, Purification & TCM Refining
Created on 08.26
Introduction: Precision Separation Starts with High-Purity Silica
In industries where purity and separation accuracy are critical—such as petrochemical refining, pharmaceutical production, and traditional Chinese medicine (TCM) processing—the performance of the separation material directly affects product quality and yield.
Column Chromatography Silica Gel is a white, uniform granular solid primarily composed of silicon dioxide (SiO₂). It is characterized by its high purity and safety. It separates and purifies different components in a mixture based on their varying retention times resulting from differential adsorption.
Whether you are refining petroleum products, removing aromatic compounds, separating active ingredients from TCM, or preparing high-purity substances, column chromatography silica gel provides reliable and repeatable performance.
What Is Column Chromatography Silica Gel?
Column chromatography silica gel is a high-purity form of silica designed specifically for chromatographic separation. It is a white, uniform granular solid with a controlled pore structure and consistent particle size.
Its separation principle is based on differential adsorption. As a mixture passes through the silica gel bed, different components travel at different speeds depending on their interaction with the silica surface. This results in different retention times, allowing individual components to be separated and collected.
Key features:
- High purity and safety
- White, uniform granular solid
- Consistent particle size distribution
- Available in industrial grade and reagent grade
- Multiple types (Type 1–4) to match different separation requirements
- Customizable mesh size
Technical Specifications
Specific Surface Area, m²/g
Grade | Type 1 | Type 2 | Type 3 | Type 4 |
Industrial | >450 | 380–600 | 300–550 | <350 |
Reagent | >450 | 380–600 | 300–550 | <350 |
Pore Volume, mL/g
Grade | Type 1 | Type 2 | Type 3 | Type 4 |
Industrial | 0.35–0.50 | 0.6–0.8 | 0.8–1.0 | >1.0 |
Reagent | 0.35–0.50 | 0.6–0.8 | 0.8–1.0 | >1.0 |
Other Specifications
Item | Specification |
Chlorides (Cl), w/% ≤ | 0.02 (reagent grade); — (industrial grade) |
Iron (Fe), w/% ≤ | 0.02 (reagent grade); — (industrial grade) |
pH (100 g/L water suspension) | Negotiable |
Loss on Heating, w/% ≤ | 5 |
Size / μm | 40–400 mesh (customizable) |
Qualified size ratio, w/% ≥ | 60 |
Note: Specifications can be customized according to your specific requirements.
Main Applications
1. Refining of Petroleum Products
Column chromatography silica gel is used in the refining of petroleum products. Its high surface area and controlled pore structure allow it to selectively adsorb impurities and unwanted compounds, improving product quality.
2. Removal of Aromatic Compounds
It is effective in the removal of aromatic compounds from mixed streams. This makes it valuable in petrochemical processing and environmental applications.
3. Separation and Purification of TCM Active Ingredients
In the traditional Chinese medicine industry, column chromatography silica gel is used to separate and purify active ingredients. Its high purity ensures that the separated compounds are not contaminated, which is critical for pharmaceutical and health product applications.
4. Preparation of High-Purity Substances
It is also used for the preparation of high-purity substances in research laboratories and industrial production. The reagent grade is particularly suitable for applications requiring strict control of chlorides and iron.
Available Grades and Types
Industrial Grade:
Suitable for large-scale petroleum refining, aromatic removal, and general separation processes.
Reagent Grade:
Higher purity with controlled chloride and iron content (≤0.02%). Suitable for TCM separation, pharmaceutical purification, and high-purity preparation.
Types 1–4:
Different types offer different specific surface areas and pore volumes, allowing users to select the optimal material for their separation challenge.
- Type 1:
High surface area (>450 m²/g), low pore volume (0.35–0.50 mL/g).
- Type 2:
Medium-high surface area (380–600 m²/g), medium pore volume (0.6–0.8 mL/g).
- Type 3:
Medium surface area (300–550 m²/g), higher pore volume (0.8–1.0 mL/g).
- Type 4:
Lower surface area (<350 m²/g), high pore volume (>1.0 mL/g).
Packaging and Customization
Standard packaging:
20 kg per compound bag.
Customization:
Packing and size can be customized per your specific requirements. We can adjust mesh size, packaging, and other parameters to match your application.
Why Choose Jusen Chem?
- Direct manufacturer:
stable supply and factory-direct pricing.
- High-purity product:
suitable for sensitive separation and purification.
- Industrial and reagent grades:
options for different purity requirements.
- Multiple types:
Type 1–4 to match various surface area and pore volume needs.
- Custom sizes:
40–400 mesh, customizable.
- Technical support:
our team can help you select the right grade and type.
- Fast delivery:
efficient logistics from China to global markets.
- Quality assurance:
products meet international standards; third-party inspection available upon request.
We are committed to supplying high-performance column chromatography silica gel for the petrochemical, pharmaceutical, and TCM industries.
FAQ
Q1: What is Column Chromatography Silica Gel used for?
It is primarily used for the refining of petroleum products, the removal of aromatic compounds, the separation and purification of active ingredients in traditional Chinese medicine (TCM), and the preparation of high-purity substances.
Q2: What is the difference between industrial grade and reagent grade?
Reagent grade has stricter purity controls, including chlorides (Cl) ≤ 0.02% and iron (Fe) ≤ 0.02%. Industrial grade is suitable for general separation and refining applications.
Q3: What are Type 1, Type 2, Type 3, and Type 4?
They refer to different combinations of specific surface area and pore volume. Type 1 has the highest surface area and lowest pore volume, while Type 4 has the lowest surface area and highest pore volume.
Q4: What sizes are available?
Standard size is 40–400 mesh. Custom sizes are available upon request.
Q5: What is the standard packaging?
Standard packaging is 20 kg per compound bag. Custom packaging is available.
Q6: Can you provide samples?
Yes, samples can be provided for evaluation. Please contact us with your specific requirements.
Contact Us
For quotations, technical data sheets, or samples of Column Chromatography Silica Gel, please contact us:
📧 Email: info@jusenchem.com
📞 WhatsApp: +86 18954690080
🌐 Website: www.jusenchem.com
Jusen Chem — your reliable partner for high-purity chromatography silica gel and separation solutions.
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